gepirone (Pending FDA Approval)

Brand and Other Names:Travivo
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Dosing & Uses

Major Depressive Disorder

Pending FDA approval for treatment of major depressive disorder

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Pharmacology

Mechanism of Action

Serotonin (5HT)-1a agonist; activation of 5HT-1a leads to glutamate inhibition; without glutamate activation of GABA interneurons, there is no inhibitory control over dopamine release, thereby, increasing dopamine release

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.