Dosing & Uses
AdultPediatric
Single Ventricle Heart Disease
Pending FDA approval for patients aged ≥12 years with single ventricle heart disease who have undergone the Fontan operation
Single Ventricle Heart Disease
Pending FDA approval for patients aged ≥12 years with single ventricle heart disease who have undergone the Fontan operation
<12 years: Safety and efficacy not established
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Pharmacology
Mechanism of Action
Inhibits PDE-5, increasing cyclic guanosine monophosphate cGMP to allow smooth-muscle relaxation
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.