phenol oropharyngeal (OTC)

Brand and Other Names:Cepastat, Ulcerease, more...Chloraseptic
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Dosing & Uses

AdultPediatric

Sore Throat

Ulcerease, Pain-A-Lay, Cloraseptic Sore Throat Gargle: Gargle or swish for 15 seconds, then expectorate; may repeat q2h

Chloraseptic: 5 sprays onto throat or affected area; may repeat q2h

Cheracol, Pain-A-Lay Spray: Spray directly in throat, rinse for 15 seconds, and expectorate; may repeat every 2 hr

Cepastat: Use up to 2 lozenges q2h PRN

Antiseptic Topical

Apply sparse amount gently to affected area once or q8-12hr

Sore Throat

Ulcerease

  • <3 years: Not established
  • >3 years: Gargle or swish for 15 seconds, then expectorate; may repeat q2h

Chloraseptic

  • <2 years: Not established
  • 2-12 years: 3 sprays onto throat or affected areas; may repeat q2h
  • >12 years: 5 sprays onto throat or affected area; may repeat q2h

Chloraseptic Kids Sore Throat

  • <2 years: Not established
  • 2-12 years: 5 sprays onto throat or affected area, may repeat q2hr
  • >12 years: Use chloraseptic formulation

Cepastat

  • <6 years: Not established
  • 6-12 years: 1 lozenge q2h PRN; not to exceed 18 lozenges/24 hours
  • >12 years: Use up to 2 lozenges q2h PRN

Cepastat Extra Strength

  • <6 years: Not established
  • 6-12 years: 1 lozenge q2h PRN; not to exceed 10 lozenges/24 hours
  • >12 years: Use up to 2 lozenges q2h PRN

Antiseptic Topical

Castellani Paint Modified

  • <12 years: Not established
  • >12 years: 1.5% (30 mL); contains acetone, basic fuchsin, ethanol 13%, resorcinol
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Adverse Effects

Frequency Not Specified

Acute epiglotitis

Edema of the epiglotitis/larynx

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Warnings

Contraindications

Documented hypersensitivity

Cautions

Overdose may cause agitation, confusion, slurred speech, and CNS depression

Do not use for sore >7 days if pain, redness, or irritation continues

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Pregnancy & Lactation

Pregnancy Category: C

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Mechanism of Action

Disinfectant, antiseptic, and local anesthetic

Pharmacokinetics

Metabolism: Metabolized to phenylglucuronide and phnyl sulfate, small amounts oxidized to catechol and quinol

Excretion: Via urine

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.