Dosing & Uses
Anemia of Chronic Kidney Disease
Pending FDA approval for treatment of anemia due to chronic kidney disease in dialysis dependent and non-dialysis dependent adults
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Pharmacology
Mechanism of Action
Hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor designed to mimic the physiologic effect of altitude on oxygen availability
At higher altitudes, the body responds to lower oxygen availability with stabilization of hypoxia-inducible factor, leading to endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells and improved oxygen delivery to tissues
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Images
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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
