rimexolone ophthalmic (Discontinued)

Brand and Other Names:Vexol (DSC)
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic solution

  • 1%

Discontinued in U.S.

Product was used for postoperative Inflammation and anterior uveitis

Safety and efficacy not established

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Adverse Effects

Frequency Not Defined

Glaucoma

Cataract

Potentiate super infection

Slow wound healing

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Warnings

Contraindications

Hypersensitivity to any component of the formulation

Herpes simplex keratitis, herpes simplex keratitis dendritic, ocular fungal disease, ocular tuberculosis, ocular viral disease

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Pregnancy & Lactation

Pregnancy Category: C

Lactation: ophthalmic corticosteroids have not been reported to cause problems in nursing babies

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

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Pharmacology

Absorption: following topical instillation of corticosteroids into the conjunctival sac, is absorbed into the aqueous humor, & systemic absorption occurs

Mechanism of Action

Synthetic nonfluorinated corticosteroid

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Images

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.