Dosing & Uses
Conjunctival Congestion
Temporary relief of ocular redness caused by irritation & relief of burning or irritation caused by dry eyes
1-2 gtt to affected eye q6-12hr
Not to exceed 72 hours of use
Administration
Remove contact lenses before use
Do not use if this solution changes color or becomes cloudy
Do not touch tip of container to any surface to avoid contamination
Replace cap after each use
Safety and efficacy not established
Adverse Effects
Frequency Not Defined
Irritation/burning
Blurred vision
Headache
Tremor
Hypertension
Tachycardia
Palpitation
Warnings
Contraindications
Hypersensitivity
Cautions
Narrow angle glaucoma
May cause temporary mydriasis
Use caution in hypertension, coronary artery disease, diabetes, and hyperthyroidism
Discontinue and seek medical advice if the following occur: eye pain, changes in vision, redness or irritation of the eye lasts >72 hr
Pregnancy & Lactation
Pregnancy Category: C
Lactation: not known if distributed in milk
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available.Pharmacology
Mechanism of Action
May stimulate alpha-adrenergic receptors in the arterioles of the conjunctiva; produces vasoconstriction
May produce mydriasis when applied to the conjunctiva, but this effect is usually minimal with the concentrations used as ocular decongestants
Pharmacokinetics
Duration: 2-3hr (vasoconstriction)
Images
| BRAND | FORM. | UNIT PRICE | PILL IMAGE |
|---|---|---|---|
| Eye Drops (tetrahydrozoline) - | 0.05 % drops |  | |
| Visine ophthalmic (eye) - | 0.05 % drops |  | |
| Redness Reliever Eye Drops - | 0.05 % drops |  |
Copyright © 2010 First DataBank, Inc.
Patient Handout
tetrahydrozoline ophthalmic (eye)
TETRAHYDROZOLINE - OPHTHALMIC
(TEH-truh-hi-DROZE-oh-leen)
COMMON BRAND NAME(S): Opti-Clear, Visine
USES: Tetrahydrozoline is a decongestant used to relieve redness in the eyes caused by minor eye irritations (e.g., smog, swimming, dust, or smoke). It belongs to a class of drugs known as sympathomimetic amines. It works by temporarily narrowing the blood vessels in the eye.Some brands of tetrahydrozoline eye drops may contain lubricants. Lubricants help protect the eyes from more irritation and dryness.
HOW TO USE: Follow all directions on the product package, or use as directed by your doctor. If you have any questions, ask your doctor or pharmacist.To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface. Remove contact lenses before applying the eye drops. Wait at least 10 minutes after using this medication before inserting contact lenses.Before using, check this product visually. Do not use if the liquid has changed color or is cloudy. Discard the medication away from children and pets.Use this medication in the affected eye(s) up to 4 times a day as needed or as directed by your doctor.Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over the eye and place 1 drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of the eye near the nose and apply gentle pressure. This will prevent the medication from draining away from the eye. Try not to blink and do not rub the eye. Repeat these steps if your dose is for more than 1 drop and for the other eye if so directed.Do not rinse the dropper. Replace the dropper cap tightly after each use. If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.Overuse of this type of medication may result in increased eye redness (rebound effect when drug wears off). If this occurs, tell your doctor. Do not use this medication for longer than 3 to 4 days at a time.If your condition persists or worsens after 72 hours, or if you think you may have a serious medical problem, stop using this medication and seek immediate medical attention.
SIDE EFFECTS: Stinging/redness in the eye, widened pupils, or blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if any of these unlikely but serious side effects occur: shakiness (tremor), fast/pounding/ irregular heartbeat, headache, sweating, weakness, nervousness.Stop using this medication and tell your doctor right away if any of these rare but very serious side effects occur: eye pain, worsening redness/itching/swelling in or around the eyes, other vision problems.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before using tetrahydrozoline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: glaucoma, heart problems (e.g., heart attack, chest pain), high blood pressure, diabetes, eye infection/injury, overactive thyroid (hyperthyroidism).This drug may cause temporary blurred vision after you apply it. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.Caution is advised when using this product in children because they may be more sensitive to the effects of the product, especially eye irritation.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug are: guanethidine, MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine), tricyclic antidepressants (e.g., amitriptyline).
OVERDOSE: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include drowsiness, severe sweating, decreased body temperature, slow/shallow breathing.
NOTES: If your symptoms are due to allergies, avoid allergens that may be the cause of your symptoms. Some common causes of allergies include pollen, grasses, weeds, dust mites, and pet dander.
MISSED DOSE: If your doctor has directed you to use this medication on a regular schedule and you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
STORAGE: Refer to storage information printed on the package. Store dropper bottle upright at room temperature between 59-77 degrees F (15-25 degrees C) away from moisture and sunlight. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised September 2021. Copyright(c) 2021 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
