Dosing & Uses
Helicobacter pylori Infection
Copackaged product indicated for treatment H pylori infection in adults
Voquezna Triple Pak contains: vonoprazan, amoxicillin, clarithromycin
Voquezna Dual Pak contains: vonoprazan, amoxicillin
Pharmacology
Mechanism of Action
Potassium-competitive acid blocker (PCAB)
Suppresses basal and stimulated gastric acid secretion at secretory surface of gastric parietal cell through inhibition of the H+, K+-ATPase enzyme system in a potassium competitive manner
Because this enzyme is regarded as the acid (proton) pump within the parietal cell, vonoprazan has been characterized as a type of gastric proton-pump inhibitor, as it blocks the final step of acid production
Does not require activation by acid.; may selectively concentrate in parietal cells in both resting and stimulated states
Binds to active proton pumps in noncovalent and reversible manner
Images
Formulary
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.