iodoquinol (Rx)

Brand and Other Names:Yodoxin
  • Print

Dosing & Uses

AdultPediatricGeriatric

Dosage Forms & Strengths

tablets

  • 210mg
  • 650mg

Intestinal Amebiasis

650 mg PO PC q8hr for 20 days; not to exceed 2 g/day

Dosage Forms & Strengths

tablets

  • 210mg
  • 650mg

Intestinal Amebiasis

30-40 mg/kg/day divided PO PC q8hr PO for 20 days; not to exceed 1.95 g/day  

Not the drug of choice (may cause optic nerve damage); use only if other therapy is contraidicated or failed

Next:

Interactions

Interaction Checker

and iodoquinol

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 

            Contraindicated (0)

              Serious - Use Alternative (6)

              • axicabtagene ciloleucel

                iodoquinol, axicabtagene ciloleucel. Either increases effects of the other by immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • brexucabtagene autoleucel

                iodoquinol, brexucabtagene autoleucel. Either increases effects of the other by immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • ciltacabtagene autoleucel

                iodoquinol, ciltacabtagene autoleucel. Either increases effects of the other by immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • idecabtagene vicleucel

                iodoquinol, idecabtagene vicleucel. Either increases effects of the other by immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • lisocabtagene maraleucel

                iodoquinol, lisocabtagene maraleucel. Either increases effects of the other by immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              • tisagenlecleucel

                iodoquinol, tisagenlecleucel. Either increases effects of the other by immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug.

              Monitor Closely (0)

                Minor (3)

                • cadexomer iodine

                  iodoquinol increases effects of cadexomer iodine by pharmacodynamic synergism. Minor/Significance Unknown.

                • iodinated glycerol

                  iodoquinol increases effects of iodinated glycerol by pharmacodynamic synergism. Minor/Significance Unknown.

                • iodine

                  iodoquinol increases effects of iodine by pharmacodynamic synergism. Minor/Significance Unknown.

                Previous
                Next:

                Adverse Effects

                Frequency Not Defined

                Headache

                Chills

                Agitation

                Diarrhea

                Rash

                Fever

                Urticaria

                Pruritus

                Thyroid gland enlargement

                Retrograde amnesia

                Nausea

                Vomiting

                Peripheral neuropathy

                Optic neuritis

                Stomach pain

                Weakness

                Visual impairment

                Optic atrophy

                Abdominal cramps

                Itching of rectal area

                Previous
                Next:

                Warnings

                Contraindications

                Hypersensitivity to 8-hydroxyquinolones or iodoquinol

                Iodine sensitivity

                Pre-existing optic neuropathy

                Hepatic damage

                Cautions

                Caution in thyroid disease

                Interferes with thyroid tests for up to 6 months after discontiunation

                Do not repeat course before 2-3 wk

                Not effective in amebic hepatitis or liver abscess

                Avoid long term thearpy (associated with optic neuritis and optic atrophy)

                Previous
                Next:

                Pregnancy & Lactation

                Pregnancy Category: C

                Lactation: unknown

                Pregnancy Categories

                A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

                B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

                C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

                D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

                X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

                NA: Information not available.

                Previous
                Next:

                Pharmacology

                Mechanism of Action

                Acts primarily in intestinal lumen; mechanism unknown

                Pharmacokinetics

                Absorption: poor & erratic

                Metabolism: Hepatic

                Excretion: Primarily feces

                Previous
                Next:

                Images

                No images available for this drug.
                Previous
                Next:

                Patient Handout

                A Patient Handout is not currently available for this monograph.
                Previous
                Next:

                Formulary

                FormularyPatient Discounts

                Adding plans allows you to compare formulary status to other drugs in the same class.

                To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

                Adding plans allows you to:

                • View the formulary and any restrictions for each plan.
                • Manage and view all your plans together – even plans in different states.
                • Compare formulary status to other drugs in the same class.
                • Access your plan list on any device – mobile or desktop.

                The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

                Tier Description
                1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
                2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
                3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
                4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
                NC NOT COVERED – Drugs that are not covered by the plan.
                Code Definition
                PA Prior Authorization
                Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
                QL Quantity Limits
                Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
                ST Step Therapy
                Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
                OR Other Restrictions
                Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
                Additional Offers
                Email to Patient

                From:

                To:

                The recipient will receive more details and instructions to access this offer.

                By clicking send, you acknowledge that you have permission to email the recipient with this information.

                Email Forms to Patient

                From:

                To:

                The recipient will receive more details and instructions to access this offer.

                By clicking send, you acknowledge that you have permission to email the recipient with this information.

                Previous
                Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.