zuranolone (Pending FDA Approval)

Brand and Other Names:
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Dosing & Uses

Major Depressive Disorder

Pending FDA approval for treatment of major depressive disorder (MDD)

Postpartum Depression

Pending FDA approval for treatment of postpartum depression (PPD)

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Pharmacology

Mechanism of Action

Oral neuroactive steroid (NAS) GABA-A receptor positive allosteric modulator (PAM)

The GABA system is the major inhibitory signaling pathway of the brain and CNS and contributes to regulating brain function (eg, mood, arousal, behavior, cognition)

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Images

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Patient Handout

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Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.