Case Challenges

A 42-Year-Old Man With Backache and Fatigue After a Divorce A 42-year-old man describes fatigue lasting 6 months after a divorce, which he attributes to depression. He also reports low back pain and feeling feverish when he wakes. What's the diagnosis?
Clinical Case, July 09, 2020
Alcoholism and Sudden Abdominal Distention in a 48-Year-Old A 48-year-old man with known cirrhosis develops increasing abdominal distention and dull pain. He also begins to experience altered mental status. What is the underlying cause of his condition?
Clinical Case, July 06, 2020
Skin Lesions and Neutropenic Fever in a 69-Year-Old Woman A 69-year-old woman presents with neutropenic fever and painful skin lesions, which began 2 weeks prior as small nodules that progressed to painful, red plaques. Can you make the diagnosis?
Clinical Case, June 26, 2020
An 8-Year-Old Boy With Autism, Lupus, Fever, and Chest Pain An 8-year old boy with autism and systemic lupus erythematosus presents to his pediatrician with fever, chest pain, and shortness of breath. Can you provide an accurate diagnosis?
Clinical Case, June 23, 2020
My Strangest Case: An Infant With Lumps in Her Belly The parents of a 3.5-month-old girl noticed lumps in her belly while bathing her. This set off an investigation into various rare diseases that could be responsible, with a surprising resolution.
Clinical Case, June 10, 2020
A 5-Year-Old With a Headache, Limp, and Projectile Vomiting A 5-year-old girl has a severe headache and projectile vomiting. Her mother says she is barely using her left arm and seems to have developed a limp in her gait recently. What's the diagnosis?
Clinical Case, June 10, 2020
A Withdrawn 14-Year-Old With Weight Loss and Sleep Problems A 14-year-old girl, described by teachers as 'fretful,' has had trouble sleeping and has lost her appetite. What's the diagnosis?
Clinical Case, June 09, 2020
A 58-Year-Old Man Unable to Maintain an Erection A 58-year-old man cannot maintain an erection. He has no difficulty with orgasm/ejaculation. He is in a stable, monogamous relationship. He does not believe underlying psychogenic factors are at work.
Clinical Case, May 21, 2020
A 22-Year-Old Who Fell Asleep on a Plane and Didn’t Wake Up A 22-year-old man with no significant medical history is transferred from the airport in a semiconscious state after returning from a 3-week vacation. What's the diagnosis?
Clinical Case, May 21, 2020
Case Report: COVID-19 in a Third-Trimester Pregnancy A woman at 38 weeks' gestation acquired COVID-19 after attending a religious event. Her case illustrates potential standard practices and questions regarding the impact of those practices on families.
Clinical Case, May 09, 2020
A 5-Year-Old Girl With High Fever and Nonproductive Cough A 5-year-old girl presents with a 2- to 3-week history of fever, cough, and occasional posttussive emesis. What's the diagnosis?
Clinical Case, May 08, 2020
A 43-Year-Old Man With Severe Itching and Hyperlipidemia A 43-year-old man who was recently diagnosed with hyperlipidemia presents with a rash that affects both axillae. He also has diffuse itching on his trunk and extremities. What's the diagnosis?
Clinical Case, May 01, 2020
A 45-Year-Old Man With Shortness of Breath, Cough, and Fever A 45-year-old HIV-positive man presents with progressive dyspnea and dyspnea on exertion, a 20-lb weight loss, and thrush. Lung imaging shows diffuse ground-glass opacities. What is the diagnosis?
Clinical Case, April 17, 2020
A 56-Year-Old Teacher With Worsening Hip Pain A 56-year-old woman with no significant past medical history presents with left hip pain. The pain would resolve with rest at first but is now continuous. Can you make this challenging diagnosis?
Clinical Case, April 06, 2020
A 25-Year-Old Woman With a Droopy Eyelid and Double Vision A 25-year-old woman with a throbbing headache developed droopiness of the left eyelid and double vision, which is gradually worsening. Can you make the diagnosis?
Clinical Case, March 20, 2020
Drinking Beer Worsens Nasal Symptoms in a 35-Year-Old Man A 35-year-old man has nasal obstruction and smelling loss. His symptoms worsen after drinking beer and also after using ibuprofen or aspirin. Can you make the diagnosis?
Clinical Case, March 12, 2020
A 46-Year-Old Man With Spine Pain and a Rash A 46-year-old man has diffuse musculoskeletal pain and swollen joints, as well as an erythematous rash in his intragluteal cleft and a scaly rash on his scalp.
Clinical Case, February 26, 2020
A 33-Year-Old Man Suddenly Unable to Stand or Sit A 33-year-old man presents owing to sudden onset of severe vertigo, vomiting, and loss of balance. He is unable to sit or stand without support. Can you make the diagnosis?
Clinical Case, February 14, 2020
An Unvaccinated Girl With Wheezing After Foreign Body Removal A 4-year-old girl with a history of developmental delay is brought to the emergency department by her parents for wheezing. Can you make the diagnosis?
Clinical Case, February 10, 2020
A 40-Year-Old Man With Dizziness, Confusion, and Neuropathy A 40-year-old man is referred for neurologic evaluation after presenting with peripheral neuropathy. He also reports dizziness associated with a 'daydreaming' feeling. What's the diagnosis?
Clinical Case, January 21, 2020

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