Case Challenges

A 26-Year-Old Woman Who Uses a Walking Cane Because of Pain A 26-year-old woman presents with severe knee pain. She now requires a cane for walking and also has a nonhealing small avulsion fracture in her right first metatarsal. Can you make the diagnosis?
Clinical Case, September 2019
A 34-Year-Old Woman With Knots on Her Leg and Reddening Skin A 34-year-old woman presents with painful, red 'knots' on her right leg that appear to trace along her veins; it started 3-4 days ago. She denies any trauma. What's the diagnosis?
Clinical Case, September 2019
A 36-Year-Old Woman With a Worsening Cough and Hearing Loss A 36-year-old woman had a worsening cough and a decrease in hearing that has been subtle over the past 6 months. Can you make this challenging diagnosis?
Clinical Case, September 2019
A 65-Year-Old Man With Diplopia and a Drooping Eyelid A 65-year-old man presents with severe, right-sided retro-orbital pain; diplopia (without visual loss); tingling on the upper half of the right side of the face; and drooping of the right eyelid.
Clinical Case, August 2019
A 22-Year-Old Man Who Lost Consciousness Climbing Stairs A 22-year-old man presents after he lost consciousness while climbing a flight of stairs. He claims that this is the first such incident. Are you able to solve this challenging case?
Clinical Case, August 2019
Worsening Abdominal Pain and Bloating in a 30-Year-Old Woman A 30-year-old woman presents with recurrent abdominal pain and loose stools. Acute worsening occurs immediately before defecation, with improvement after defecation. What's the diagnosis?
Clinical Case, August 2019
A 65-Year-Old Man Brought to the ED by Military Police A 65-year-old man is brought to the ED by military police after an armed standoff. Can you determine what medical condition is most likely involved?
Clinical Case, August 2019
A 38-Year-Old Woman With Debilitating Premenstrual Pain A woman presents with a 2-year history of an abdominal wall mass that has recently enlarged in size, with associated soreness and pain, and a 3-year history of menstrual issues. What is the diagnosis?
Clinical Case, July 2019
Dramatic Weight Loss in a Patient With Parkinson Disease A 67-year-old man who was diagnosed with Parkinson disease has experienced recent unintentional weight loss. Do you know how best to proceed with his care?
Clinical Case, July 2019
A 19-Year-Old Shooting Victim With Complications Five weeks after polytrauma from multiple gunshot wounds, a 19-year-old man is experiencing diffuse right-sided chest pain and shortness of breath. Can you make the diagnosis?
Clinical Case, July 2019
A 77-Year-Old Retired Teacher With a Constant Headache A 77-year-old retired teacher presents to the emergency department with dizziness, imbalance, nausea/vomiting, and a constant headache for the past 2 weeks. Can you make the diagnosis?
Clinical Case, July 2019
A 12-Year-Old Boy With Falling Grades and Forgetful Behavior A 12-year-old boy with declining grades is disruptive at school, forgetful at home, and upset by tasks that are time consuming or cognitively demanding.
Clinical Case, June 2019
A 45-Year-Old Woman Who Feels 'Like a Zombie' A 45-year-old woman states that she feels 'like a zombie.' She has experienced continued confusion and sedation long after a respiratory illness resolved. Can you make the diagnosis?
Clinical Case, June 2019
A 14-Year-Old Boy With Unexplained, Recurring Fever A 14-year-old boy presents with a 2-week history of unrelenting fever and generalized fatigue. What is the most likely diagnosis?
Clinical Case, June 2019
A 20-Year-Old Woman With Nail Abnormalities and Vomiting A 20-year-old woman presents with flank pain and vomiting, along with periungual fibromas. What's the diagnosis?
Clinical Case, June 2019
A 26-Year-Old Man Who Passed Out at His Work Desk Paramedics bring a 26-year-old man to the ED with acute-onset altered mental status. He has a history of back pain. An open, unlabeled pillbox was found. An ECG is ordered. What is the diagnosis?
Clinical Case, May 2019
A 64-Year-Old Man Unable to Lift His Arm or Walk A 64-year-old man presents with left-sided weakness that has worsened to the point where he cannot comfortably walk or lift his arm. What's the diagnosis?
Clinical Case, May 2019
A 29-Year-Old Woman With Worsening Pain and Memory Issues A 29-year-old woman presents with multiple joint and muscle pain, back pain, and increasing fatigue. She is also suffering from depression, as well as memory and concentration problems.
Clinical Case, May 2019
A 31-Year-Old Woman With Right Arm Tremors A 31-year-old woman has had tremors in her right hand and arm over the past month. She is otherwise in good health and has not needed to see a doctor in years. Can you make the diagnosis?
Clinical Case, May 2019
A 17-Year-Old Athlete in Cardiac Arrest A 17-year-old boy drops to the ground and is unresponsive after being elbowed by a teammate who ran into him. CPR is initiated, and the patient is taken to the ED. What is the likely diagnosis?
Clinical Case, April 2019

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