Setting Treatment Goals in Psoriatic Arthritis

Philip Mease, MD


September 22, 2022

Setting treatment goals in psoriatic arthritis can be challenging given the broad range of psoriatic arthritis (PsA) symptoms, says Dr Philip Mease of Swedish Medical Center in Seattle, and that has led experts to recommend a treat-to-target approach in this condition.

Dr Mease reviews standards set by Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Disease Activity in Psoriatic Arthritis (DAPSA) that can help guide physicians to set goals in PsA and discusses the TICOPA trial, the results of which support treat-to-target methodology.

Complicating the PsA goal-setting equation, patients and clinicians may not always agree on what the treatment target should be. Dr Mease reports on recent focus groups that found both patients and physicians ranked pain and improvement of function as high priorities, but patients also considered fatigue, sleep disturbance, access to care, and long-term treatment efficacy of great importance. Dr Mease emphasizes that treatment goals should be determined by shared decision-making to reflect the patient's priorities.


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