Peripheral Neuropathy in Type 2 Diabetes

Rodica Pop-Busui, MD, PhD


April 24, 2023

About half of people with type 2 diabetes develop peripheral neuropathy, which comes with progressive loss of sensation and increased risk for falls, foot ulcers, and amputation.

Prevention of peripheral neuropathy involves regular risk factor control of glucose, obesity, lipids, and blood pressure. However, once neuropathy begins, there is no effective way to reverse this condition.

In this ReCAP, Dr Rodica Pop-Busui, from the University of Michigan, outlines simple office screening techniques to detect peripheral neuropathy and recommended pharmacologic and nonpharmacologic treatments for neuropathic pain. She emphasizes that opioids should be avoided because of the high mortality and addiction risk, as well as the lack of efficacy.


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