Fast Five Quiz: Do You Know the Basics and Best Practices for Adjuvant Therapy in Breast Cancer?

Mary Denshaw-Burke, MD


September 03, 2020

Joint pain (arthralgia) and muscle pain (myalgia) are common side effects of aromatase inhibitors. Almost half of women taking aromatase inhibitors have joint pain and about 15% have muscle pain. Joint and muscle pain can mimic carpal tunnel syndrome. In rare cases, aromatase inhibitors can cause carpal tunnel syndrome. Although aromatase inhibitors can cause joint and muscle pain, they don’t cause permanent joint or muscle damage.

Aromatase inhibitors cause a loss of bone density. Changes to bone density should be monitored and risk for fracture should be assessed in regard to exercise and calcium/vitamin D supplementation recommendations.

Menopausal symptoms such as hot flashes and night sweats are common in women who take aromatase inhibitors. Although these symptoms may become less frequent and less intense over time, they can still be hard to manage.

Learn more about aromatase inhibitors.


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