Topical 5-fluorouracil 5% cream may be used to treat small, superficial BCCs in low-risk areas. It interferes with DNA synthesis by blocking methylation of deoxyuridylic acid and inhibiting thymidylate synthetase and, subsequently, cell proliferation. In properly selected (ie, thin) tumors, cure rates of approximately 80% have been obtained.
For more on topical treatments for BCC, read here.
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Cite this: Basal Cell Carcinoma Fast Five Quiz: How Familiar Are You With Identification and Treatment? - Medscape - Jul 02, 2014.
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