Prostate cancer grading has traditionally been performed according to the Gleason Grading system, which is on the basis of histologic evaluation of tumor biopsy specimens. It is a two-number system in which the first number is assigned to the predominant focus of tumor and the second assigned to the second more predominant pattern; each is graded on a scale of 1-5, and the sum of the two constitutes the overall grade. Generally, the cutoff for prostate cancer starts with Gleason grade 3 + 3 cancer.
A score of 2-6 indicates a low-grade or well-differentiated tumor
A score of 7 indicates a moderate-grade or moderately differentiated tumor
A score of 8-10 indicates a high-grade or poorly differentiated tumor
Learn more about the workup for prostate cancer.
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Cite this: Fast Five Quiz: Do You Know the Current Guidelines for the Screening and Treatment of Prostate Cancer? - Medscape - Apr 18, 2022.