Fast Five Quiz: How Prepared Are You to Address Chronic Myelogenous Leukemia?

Emmanuel C. Besa, MD


November 11, 2014

The Philadelphia chromosome is the result of a reciprocal translocation between the long arms of chromosomes 9 and 22. During this process, the ABL oncogene is transferred from chromosome 9 to 22. This results in the formation of the BCR/ABL fusion gene. This fusion gene encodes for a protein with strong tyrosine kinase activity.

To read more on the pathophysiology of chronic myelogenous leukemia, click here.


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