Fast Five Quiz: Can You Properly Identify Ulcerative Colitis and Initiate Best Treatment?

Marc D. Basson, MD, PhD, MBA; Leyla Ghazi, MD


February 08, 2023

Figure 2. Topical mesalamine given by suppository is preferred in mild disease.

In mild disease confined to the rectum, topical mesalamine given by suppository is the preferred therapy. Enemas and foams are less effective because their concentration in the rectum rapidly diminishes. Left-sided colonic disease is best treated with a combination of mesalamine suppository and an oral aminosalicylate. Systemic steroids are indicated when disease fails to respond quickly to aminosalicylates.

Learn more about the treatment of ulcerative colitis.


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