Bacterial infection is the leading cause of death in patients with myeloma. Poor prognostic factors include the following:
Bence Jones proteinemia
Renal impairment (ie, stage B disease or creatinine level > 2 mg/dL at diagnosis)
The prognosis by treatment is as follows:
Conventional therapy: Overall survival is approximately 3 years, and event-free survival is less than 2 years.
High-dose chemotherapy with stem cell transplantation: The overall survival rate is greater than 50% at 5 years.
Serum amyloid P retention: More than 50% of patients have a median survival of approximately 11 months.
Learn more about the prognosis of multiple myeloma.
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Cite this: Emmanuel C Besa, Dhaval Shah. Fast Five Quiz: Are You Prepared to Confront Multiple Myeloma? - Medscape - Jan 14, 2022.