Fast Five Quiz: Are You Prepared to Confront Multiple Myeloma?

Emmanuel C Besa, MD; Dhaval Shah, MD


January 14, 2022

Bacterial infection is the leading cause of death in patients with myeloma. Poor prognostic factors include the following:

  • Tumor mass

  • Hypercalcemia

  • Bence Jones proteinemia

  • Renal impairment (ie, stage B disease or creatinine level > 2 mg/dL at diagnosis)

The prognosis by treatment is as follows:

  • Conventional therapy: Overall survival is approximately 3 years, and event-free survival is less than 2 years.

  • High-dose chemotherapy with stem cell transplantation: The overall survival rate is greater than 50% at 5 years.

  • Serum amyloid P retention: More than 50% of patients have a median survival of approximately 11 months.

Learn more about the prognosis of multiple myeloma.


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