Current guidelines identify the following groups as deriving the most benefit from statin therapy:
Individuals who have established clinical ASCVD, which is defined as proven coronary heart disease (CHD), stroke, or peripheral arterial disease of atherosclerotic origin: High-intensity or moderate-intensity statin therapy should be initiated, depending on age.
Individuals with LDL-C levels of 190 mg/dL or higher who are likely to have familial hypercholesterolemia: High-intensity statin therapy should be initiated unless they are not candidates, in which case moderate-intensity statin therapy should be started.
Individuals age 40-75 years with diabetes mellitus (type 1 or 2) and LDL-C levels of 70-189 mg/dL: Moderate-intensity statin therapy is indicated, unless the estimated 10-year ASCVD risk is 7.5% or higher.
Individuals who do not have ASCVD or diabetes mellitus, who are age 40-75 years, and who have an estimated 10-year ASCVD risk of 7.5% or higher: Moderate-intensity to high-intensity statin therapy is indicated.
For more on statin use, read here.
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Cite this: Yasmine S. Ali, Mary Ellen T. Sweeney. Fast Five Quiz: Do You Know Current Guidelines for Lipid Management? - Medscape - May 19, 2015.
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