Fast Five Quiz: Are You Familiar With Stress-Related Medical Conditions?

Richard H. Sinert, DO


August 28, 2015

At present, sedative-hypnotics remain the most commonly prescribed sleep medications. Suvorexant (Belsomra®) was approved by the US Food and Drug Administration (FDA) in August 2014 and is the first orexin receptor antagonist for insomnia. It is indicated for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. Ramelteon (Rozerem®), a melatonin receptor agonist, has been approved by the FDA for use in persons with insomnia. It has been shown to have no potential for abuse and, as such, is the first nonscheduled prescription drug available in the United States for the treatment of insomnia.

Antihistamines are the active ingredients in over-the-counter sleep aids and in cold and sinus formulas sold as bedtime-use medications. Nevertheless, common antihistamines (ie, first-generation H1-receptor antagonists such as diphenhydramine, hydroxyzine, and doxylamine) are not indicated for the treatment of sleeplessness.

For more on insomnia treatments, read here.


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