Fast Five Quiz: Do You Know Best Practices for Osteoporosis?

Herbert S. Diamond, MD


November 12, 2020

The workup for osteoporosis consists of laboratory studies to establish baseline values, along with measurement of bone mineral density (BMD) to assess bone loss and estimate the risk for fracture. Additionally, because occult disorders are so common in patients with osteoporosis, laboratory screening to assess for secondary causes is important. Antigliadin and antiendomysial antibodies can help to identify patients with celiac disease, which is associated with major osteoporotic fracture.

Other secondary causes of osteoporosis to exclude include hypercalciuria and hypocalciuria; benign familial hypocalciuric hypercalcemia; subclinical hypothyroidism and hyperthyroidism; sex hormone deficiency (in younger men with osteoporosis); Cushing syndrome; multiple myeloma; and mastocytosis. When a hematologic disorder is suspected, a bone marrow biopsy should be performed.

Learn more about the workup of osteoporosis.


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