
As a general rule, asymptomatic hyperuricemia should not be treated. Patients with levels higher than 11 mg/dL who overexcrete uric acid are at risk for renal stones and renal impairment; therefore, renal function should be monitored in these individuals. Tophi should not be surgically removed unless they are in a critical location or drain chronically.
Although colchicine was once the treatment of choice for acute gout, it is now less commonly used than nonsteroidal anti-inflammatory drugs because of its narrow therapeutic window and risk for toxicity. To be effective, colchicine therapy is ideally initiated within 36 hours of onset of the acute attack.
For more the treatment of gout, read here.
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Cite this: Herbert S. Diamond. Fast Five Quiz: Are You Prepared to Confront Gout? - Medscape - Dec 10, 2015.
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