Approximately 95% of prostate cancers are adenocarcinomas. Ductal carcinoma and neuroendocrine carcinoma account for the majority of additional cases.
Squamous cell carcinomas constitute < 1% of all prostate carcinomas. In many cases, prostate carcinomas with squamous differentiation arise after radiation or hormone treatment. Of prostate cancer cases, 70% arise in the peripheral zone, 15%-20% arise in the central zone, and 10%-15% arise in the transitional zone. Most prostate cancers are multifocal, with synchronous involvement of multiple zones of the prostate, which may be owing to clonal and nonclonal tumors.
Learn more about the pathophysiology of prostate cancer.
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Cite this: Bradley Schwartz. Fast Five Quiz: Check Your Knowledge of Prostate Cancer - Medscape - Apr 18, 2022.
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