Clinical Trends for March 2016

Ryan Syrek

Disclosures

March 25, 2016

Clinical Trend of the Week (February 27 - March 4): PPI Dementia

A new study confirming an association between proton pump inhibitors (PPIs) and an increased risk for dementia drove searches this week. PPIs are incredibly popular, especially among older patients. In an analysis of 73,769 subjects aged 75 years or older who did not have dementia at baseline, 29,510 were diagnosed with at least one form of dementia, with more than half having two different types. Of those found to have dementia, 2950 were regularly using a PPI. Given the vast number of elderly patients taking PPIs and the fear of declining mental faculties, physicians will likely continue to monitor new findings for guidance in treating their patients.

For more in-depth clinical information, see Gastroesophageal Reflux Disease.

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