In a multicenter, prospective, observational study of 201 consecutive patients with moderate-to-severe COPD, Martinez-Garcia and colleagues reported that in addition to smoking, pulmonary hypertension, and declining lung function, all of which are known risk factors for mortality in patients with COPD, bronchiectasis, which is common in patients with moderate-to-severe COPD, is independently associated with increased risk for all-cause mortality.
In this study, those who had bronchiectasis were found to be 2.5 times more likely to die than those who did not. Bronchiectasis remained an independent risk factor after adjustment for dyspnea, partial pressure of oxygen, body mass index, presence of potentially pathogenic micro-organisms in sputum, presence of daily sputum production, number of severe exacerbations and peripheral albumin, and ultrasensitive C-reactive protein concentrations.
For more on the prognosis of COPD, read here.
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Cite this: Amanda M. K. Godfrey, Zab Mosenifar. Fast Five Quiz: How Much Do You Know About COPD? - Medscape - May 27, 2020.