In a systematic review of five studies of noninvasive screening tools for detecting peripheral neuropathies in pediatric patients with type 1 diabetes, Hirschfeld and colleagues found that the diagnostic utility of the Rydel-Seiffer tuning fork and 10-g Semmes-Weinstein monofilament was low, while that of biothesiometry and a finer (1-g) monofilament was acceptable. Sensitivities and specificities of these screening tools were as follows:
Tuning fork: 87-99% (sensitivity); 1-19% (specificity)
Coarse monofilament: 16% (sensitivity); 64% (specificity)
Fine monofilament: 73% (sensitivity); 87% (specificity)
Biothesiometer: 61-80% (sensitivity); 64-76% (specificity)
For more on presentation of diabetic neuropathy, read here.
Medscape © 2016 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Dianna Quan, Romesh Khardori. Fast Five Quiz: How Much Do You Know About Diabetic Neuropathy? - Medscape - Jul 13, 2016.