Psoriasis is a complex, chronic, multifactorial, inflammatory disease that involves hyperproliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate. Environmental, genetic, and immunologic factors appear to play a role. The disease most commonly manifests on the skin of the elbows, knees, scalp, lumbosacral areas, intergluteal clefts, and glans penis. In as many as 30% of patients, the joints are also affected.
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Cite this: Dirk M Elston, William James. Fast Five Quiz: What Do You Know About Psoriasis? - Medscape - Jan 25, 2023.