Fast Five Quiz: What Do You Know About Psoriasis?

Dirk M Elston, MD; William James, MD


June 13, 2019

Recommendations for the treatment of moderate to severe plaque psoriasis include the following:

  • Methotrexate may be used for as long as it remains effective and well tolerated.

  • Cyclosporine is generally used intermittently for inducing a clinical response with one or several courses over a 3- to 6-month period.

  • Transition from conventional systemic therapy to a biologic agent may be done directly or with an overlap if transitioning is needed because of lack of efficacy, or with a treatment-free interval if transitioning is needed for safety reasons.

  • Combination therapy may be helpful.

  • Continuous therapy for patients receiving biologics is recommended.

  • Switching biologics because of lack of efficacy should be performed without a washout period, while switching biologics for safety reasons may require a treatment-free interval.

For more on the treatment of psoriasis, read here.

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