Neuroimaging is unlikely to detect brain lesions in patients with clinical and EEG features of idiopathic generalized epilepsy or benign rolandic epilepsy. King and coworkers found that MRI did not detect any brain lesions in 49 patients with clinical and EEG features of idiopathic generalized epilepsy or in 11 patients with benign rolandic epilepsy.
Studies have shown a low yield for extensive laboratory tests in the evaluation of a patient presenting with a first-time single seizure.
Patients with generalized tonic-clonic seizures and idiopathic generalized epilepsy typically have no evidence of any localized, regional, or diffuse brain abnormality on history, physical, or neurologic examination; clinical laboratory testing; or imaging studies.
CT may miss surgically remedial brain lesions that would otherwise be detected by MRI.
For more on the workup of seizures, read here.
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Cite this: Amy Kao, Helmi L Lutsep. Fast Five Quiz: Test Your Knowledge of Various Seizures and Their Causes - Medscape - Apr 03, 2017.