Clinical Trends for April 2017

Ryan Syrek

Disclosures

April 28, 2017

Clinical Trend of the Week (April 15-21): Menopause

This week's top search term was "hot" for several reasons. A study published in the journal Menopause found that frequent hot flashes, a common symptom of menopause, in a certain group may be associated with emerging vascular dysfunction that could lead to heart disease. The study included 272 nonsmoking women (age 40-60 y) and found that early occurring hot flashes (age 40-53 y) may be most relevant to the risk for heart disease. Meanwhile, at the 2017 Endocrine Society Annual Meeting, a new treatment option for hot flashes was discussed. Phase 2 data from two trials found that treatment with neurokinin 3 (NK3) receptor antagonists may significantly relieve symptoms of hot flashes without estrogen exposure. This significant cardiovascular association with symptoms of menopause and potential treatment for those symptoms will continue to receive plenty of attention.

For more information on menopause, read here.

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