Fast Five Quiz: Test Your Knowledge of Mantle Cell Lymphoma

Elwyn C Cabebe, MD; Winston W. Tan, MD; Ann S. LaCasce, MD, MMSc

Disclosures

January 09, 2023

Figure 1. Patient with affected lymph node.

Stage III or IV disease is present in 70%-80% of MCL cases at presentation.

Findings on the history may include:

B symptoms, which include fever, night sweats, and weight loss, in 40% of patients
Generalized lymphadenopathy
Abdominal distention from hepatosplenomegaly
Fatigue from anemia or bulky disease
Less common symptoms caused by extranodal involvement of gastrointestinal tract and lungs

Physical examination findings may include:

Generalized lymphadenopathy in 90%
Splenomegaly in 60% (may be massive)
Hepatomegaly in 30%
Poor performance status in 20%
Gastrointestinal tract involvement in 26%
CNS involvement (though rare)

Learn more about MCL.

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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.

Cite this: Elwyn C Cabebe, Winston W. Tan, Ann S. LaCasce. Fast Five Quiz: Test Your Knowledge of Mantle Cell Lymphoma - Medscape - Jan 09, 2023.

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