Dengue is the most common arthropod-borne viral (arboviral) illness in humans. Annually, approximately 50-100 million individuals are infected. The Centers for Disease Control and Prevention reports that cases of dengue in returning US travelers have increased steadily during the past 20 years, and dengue has become the leading cause of acute febrile illness in US travelers returning from the Caribbean, South America, and Asia.
Dengue is transmitted by mosquitoes of the genus Aedes, which are widely distributed in subtropical and tropical areas of the world. A small percentage of persons who have previously been infected by one dengue serotype develop bleeding and endothelial leak upon infection with another dengue serotype. This syndrome is termed "dengue hemorrhagic fever."
Dengue fever is typically a self-limited disease, with a mortality rate of less than 1%. When treated, dengue hemorrhagic fever has a mortality rate of 2%-5%, but when left untreated, the mortality rate is as high as 50%.
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Cite this: Fast Five Quiz: Test Your Knowledge of Dengue and Related Conditions - Medscape - Jul 27, 2017.