Although aqueous tear deficiency is a common cause of dry eye, and is due to insufficient tear production, the major cause of dry eye is evaporative loss due to meibomian gland dysfunction, according to research presented in the Tear Film & Ocular Surface Society International Dry Eye Workshop II (TFOS DEWS II). Low blink rate and ocular allergy are also causes of evaporative loss, although meibomian gland dysfunction is the most common cause.
Causes of deficient aqueous production include the following:
Dry eye associated with Sjögren syndrome (primary and secondary)
Lacrimal gland deficiency
Lacrimal gland duct obstruction
For more on dry eye disease, read here.
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Cite this: Fast Five Quiz: Are You Familiar With Dry Eye Disease? - Medscape - Sep 29, 2017.