Fast Five Quiz: Test Your Knowledge of Soft-Tissue Sarcomas

Elwyn C. Cabebe, MD; Derek B. Laskar, MD


January 03, 2018

The histologic appearance shows a highly cellular fibroblastic proliferation of cells in parallel sheets arranged in intertwining whorls; this is commonly referred to as "herringbone architecture." Grossly, the tumors are fleshy, hemorrhagic, and necrotic.

For fibrosarcoma, bone scanning has largely been supplanted by MRI. The main limitation of bone scanning is that it often is nonspecific. Bone scanning with technetium-99m is a very useful adjunct in the evaluation of tumor stage. It aids in the detection of bone metastatic or polyostotic disease.

Plain radiographs of the involved anatomical region are needed to evaluate for primary or secondary involvement of bone. For soft-tissue masses, size often can be estimated, any bone involvement can be seen, and intralesional content (matrix) can sometimes be determined.

Some authors have suggested the use of gallium and ultrasound for diagnosis. At present, the value of these tests for staging of sarcomas remains limited.

For more on the workup of fibrosarcoma, read here.


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