Fast Five Quiz: How Much Do You Know About 'Broken-Heart Syndrome'?

Yasmine S. Ali, MD, MSCI


January 22, 2018

Takotsubo cardiomyopathy has been reported after near-drowning episodes. Seizures may also trigger Takotsubo cardiomyopathy, but it is rare for Takotsubo cardiomyopathy to result in SUDEP. Recognized stressors include:

  • Learning of the death of a loved one

  • Bad financial news

  • Legal problems

  • Natural disasters

  • Motor vehicle collisions

  • Exacerbation of a chronic medical illness

  • Newly diagnosed, significant medical condition

  • Surgery

  • Intensive care unit (ICU) stay

  • Use of or withdrawal from illicit drugs

The International Takotsubo Registry reported that patients with Takotsubo cardiomyopathy, as compared with patients who had acute coronary syndrome (ACS), were more likely to be female (89.8%) and that physical triggers were more common than emotional triggers (36% vs 27.7%), although more than one quarter (28.5%) had no clear triggers. Patients with Takotsubo cardiomyopathy also had higher rates of neurologic or psychiatric disorders and a significantly lower LV ejection fraction (LVEF). The two groups had similar rates of severe inpatient complications (eg, shock, death), and independent predictors of such complications included physical triggers, acute neurologic/psychiatric diseases, elevated troponin levels, and low LVEF.

For more on Takotsubo cardiomyopathy, read here.


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