cN3 indicates metastases in ipsilateral infraclavicular (level III axillary) lymph node(s)—with or without level I, II axillary node involvement—or in ipsilateral internal mammary lymph node(s) with level I, II axillary lymph node metastasis; or metastasis in ipsilateral supraclavicular lymph node(s), with or without axillary or internal mammary lymph node involvement.
cN1 indicates metastasis to movable ipsilateral level I, II axillary lymph node(s).
cN2 indicates metastases in ipsilateral level I, II axillary lymph nodes that are clinically fixed or matted, or in ipsilateral internal mammary nodes in the absence of clinically evident axillary lymph node metastasis.
pN1 indicates micrometastases or metastases in one to three axillary lymph nodes and/or in internal mammary nodes; and/or in clinically negative internal mammary nodes with micrometastases or macrometastases by sentinel lymph node biopsy.
pN2 indicates metastases in four to nine axillary lymph nodes; or positive ipsilateral internal mammary lymph nodes by imaging in the absence of axillary lymph node metastases.
cM1 indicates distant detectable metastases determined by clinical and radiographic means.
Learn more about breast cancer staging.
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Cite this: Elwyn C. Cabebe. Fast Five Quiz: Key Aspects of Metastatic Breast Cancer - Medscape - Aug 10, 2020.
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