GINA guidelines state that approximately 50% of patients with severe asthma have type 2 inflammation. Type 2 inflammation is characterized by eosinophils, increased FeNO, and cytokines (eg, interleukin [IL]-4, IL-5, IL-13).
Neutrophils are characteristic of non–type-2 inflammation, as is rapid improvement with correct and regular use of inhaled corticosteroids.
For more on the presentation of asthma, read here.
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Cite this: Zab Mosenifar. Fast Five Quiz: Test Your Knowledge of Severe Asthma - Medscape - May 18, 2020.