Misdiagnosis of asthma reportedly occurs in as many as 30% of cases. Alternate diagnoses such as chronic obstructive pulmonary disease, left ventricular failure, localized obstruction, cystic fibrosis, and/or vocal cord dysfunction should be excluded.
According to updated ERS/ATS guidelines, high-resolution CT should only be performed in patients with atypical presentations of severe asthma. In adults with severe asthma, treatment should be guided by both sputum eosinophil counts and clinical criteria. These guidelines do not suggest use of exhaled nitric oxide to guide therapy in patients with severe asthma.
For more on the workup and laboratory studies of patients with severe asthma, read here.
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Cite this: Zab Mosenifar. Fast Five Quiz: Test Your Knowledge of Severe Asthma - Medscape - May 18, 2020.