Amyloidosis is characterized by the accumulation of fibrillar proteins in various body tissues. Before the early 1970s, historical classification systems of amyloidosis were based on clinical signs of the disease and the organs affected; however, such systems were descriptive and did not provide insight into etiology. The development of methods to solubilize and perform chemical studies on amyloid fibrils led to modern classification systems, which are based on approximately 30 different known protein types.
Because there are diverse clinical manifestations of amyloidosis, and because symptoms are often nonspecific, diagnosis can be challenging. As a result, amyloidosis is often underdiagnosed or not diagnosed until later stages of the disease.
Are you familiar with the classification, presentation, diagnosis, and treatment of amyloidosis? Check your knowledge with our short quiz.
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Cite this: Herbert S. Diamond. Fast Five Quiz: How Much Do You Know About Amyloidosis? - Medscape - Nov 02, 2018.