Fast Five Quiz: How Much Do You Know About Chronic Inflammatory Demyelinating Polyradiculoneuropathy?

Jafar Kafaie, MD, PhD

Disclosures

February 08, 2019

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare acquired, progressive, immune-mediated peripheral neuropathic disease that is more common in adults than in children. Untreated, undiagnosed, and delayed-diagnosed cases of CIDP are associated with significant, irreversible disability; therefore, early diagnosis and treatment are essential.

The majority of patients with CIDP experience progressive worsening of symptoms, from which they may experience phases of intermittent partial or complete recovery. Although most cases of CIDP are insidious in onset, approximately 16% of patients experience acute-onset CIDP, the presentation of which is similar to that of Guillain-Barré syndrome (GBS).

Similar to acute inflammatory demyelinating polyradiculoneuropathy (a demyelinating type of GBS), segmental and patchy demyelination of peripheral nerves leads to relatively symmetrical sensory and motor deficits in the classic forms of CIDP. It is important to differentiate between these two distinct conditions to ensure appropriate management and treatment.

Owing to the slow evolution of the disease and partial or complete recovery of symptoms between recurrences, CIDP can be challenging to diagnose. Are you familiar with signs and symptoms, pathophysiology, presentation, workup, and treatment of this devastating illness? Test your knowledge with this short quiz.

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