Fast Five Quiz: Imaging Studies in Metastatic Bone Disease

Maurie Markman, MD


March 27, 2019

The presence of a halo sign, or bull's-eye sign, on MRI helps to distinguish MBD from benign lesions. Additionally, MRI of the spine can demonstrate posterior vertebral body bulging, signal-intensity changes extending into the pedicle, and paraosseous tumor spread (into the soft tissue).

When palpating a patient's radial artery using the Osler maneuver, the presence of the Osler sign, or pseudohypertension, indicates a falsely elevated blood pressure due to a noncompressible artery resulting from calcification of the blood vessels.

The Bancroft sign, or Moses sign, occurs when calf compression on the tibia elicits a painful response on examination, and is a clinical sign of DVT of the posterior tibial veins. The sign is positive when the calf is compressed anteriorly, but not when compressed side to side.

The Battle sign is bruising over the mastoid process following fracture of the middle cranial fossa of the skull. This sign is associated with brain trauma.

For more on the role of MRI studies in MBD, read here.


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