Fast Five Quiz: Can You Diagnose Waldenström Macroglobulinemia?

Emmanuel C. Besa, MD


March 13, 2019

The REAL and WHO classifications define WM as a rare, chronic, slowly progressive lymphoplasmacytic lymphoma due to a mutation in B lymphocytes. This mutation causes an overproduction of IgM, resulting in HVS and lymphoplasmacytic infiltrate in the bone marrow.

WM is not a form of chronic obstructive pulmonary disease, chronic lymphocytic leukemia, or fibroblastic sarcoma.

For more on the pathophysiology of WM, read here.


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