Fast Five Quiz: How Much Do You Know About Diagnosing and Treating Metastatic Colorectal Cancer?

Elwyn C. Cabebe, MD


July 02, 2019

Adenocarcinomas represent 96%-98% of CRC. Carcinoid tumors, lymphomas, and sarcomas are comparatively rare in CRC, and primary adenosquamous and squamous cell carcinomas are extremely rare.

More than one half of all CRCs develop in the rectum and sigmoid colon. With respect to metastatic CRC, a 2015 study by Augestad and colleagues found an association between the primary CRC site and that of future metastasis. In this study, the authors found that patients whose CRC was located on the left side had a 70% increased risk of developing isolated liver metastasis, and patients with rectal cancer had a greater than twofold increased risk for not only primary site recurrence but also isolated lung metastasis.

For more on the pathophysiology of CRC, read here.


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