Fast Five Quiz: How Much Do You Know About HIV Pre- and Postexposure Prophylaxis?

Jason F. Okulicz, MD


July 15, 2019

All patients should have a negative HIV-1 test immediately before starting PrEP. Any patient with signs of acute viral infection that may be indicative of acute HIV infection and recent (<1 month) HIV exposure should be retested for HIV-1 at least 1 month later. If the second test is negative, the patient can be started on PrEP.

Individuals whose partners have a confirmed HIV infection are considered to be at high risk of contracting the virus. Patients may also be considered at high risk if they are sexually active in a social network or area in which there is a high prevalence of HIV, and if they have one or more of the following:

  • Other STIs

  • Alcohol or illicit drug dependence

  • Inconsistent or no condom use

  • Exchanged sex for commodities such as shelter, drugs, food, or money

  • Incarceration

  • Partner or partners of unknown HIV status with any of these factors

For more on evaluating patients to determine whether they are at high risk for HIV transmission and for whom PrEP is indicated, read here.


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