Fast Five Quiz: How Much Do You Know About HIV Pre- and Postexposure Prophylaxis?

Jason F. Okulicz, MD


July 15, 2019

Although the US Public Health Service previously advised that ARV prophylaxis decisions should be based on the extent and severity of the exposure, the updated guidelines recommend PEP treatment with three or more ARVs for any type of exposure. Several combinations of ARVs may fulfill this requirement; however, the preferred HIV PREP regimen is raltegravir twice daily plus FTC/TDF once daily.

The US Public Health Service guidelines also provide a list of alternative HIV PEP regimens. These involve one pair of nucleoside/nucleotide reverse transcriptase inhibitors in combination with one drug or drug pair from the protease inhibitor, integrase strand transfer inhibitor, or nonnucleoside reverse transcriptase inhibitor classes.

For more on treatment options for patients after an occupation-related HIV exposure, read here.


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