Bone-targeting agents are frequently prescribed to patients receiving palliative treatment for metastatic prostate cancer. Therefore, patients receiving ADT and those with bone metastasis should receive preventive therapy for fractures. Patients diagnosed with impending paralysis due to spinal cord compression or patients with pathologic fractures require immediate hospitalization and emergent treatment with spinal cord decompression, corticosteroid therapy, and orchiectomy, a luteinizing hormone–releasing hormone (LHRH) antagonist, an antiandrogen, or ketoconazole.
Androgens are contraindicated in patients with metastatic prostate cancer. As previously noted, patients with metastatic prostate cancer receive palliative ADT.
Estrogen is not used in the treatment of prostate cancer.
TKIs are not currently indicated as a treatment for prostate cancer.
For more on palliative therapy for patients with metastatic prostate cancer, read here.
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Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Bradley Schwartz. Fast Five Quiz: How Much Do You Know About Prostate Cancer Treatment? - Medscape - Apr 04, 2019.