Tardive dyskinesia (TD), according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), is a medication-induced movement disorder that causes involuntary repetitive muscle movements in the face, neck, arms, and legs that persist despite discontinuation or change in medication. TD primarily occurs as a side effect of long-term use of dopaminergic antagonist medications, making patients with schizophrenia or bipolar disorder treated with antipsychotics most susceptible to developing TD. However, patients with developmental disabilities or other neurologic disorders may be exquisitely vulnerable to develop TD with minimal exposure to low doses of dopamine-blocking medications. The abnormal, involuntary movements of TD can significantly affect quality of life, making routine physical functioning difficult. Thus, clinicians should have a clear understanding of causative agents associated with TD and optimal treatment strategies.
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Cite this: Matthew Swan, James Robert Brasic. Fast Five Quiz: How Much Do You Know About Tardive Dyskinesia? - Medscape - Apr 22, 2022.
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