Fast Five Quiz: Key Aspects of Hypothyroidism

Romesh Khardori, MD, PhD


April 15, 2019

Hypothyroidism commonly manifests as a slowing in physical and mental activity but patients may be asymptomatic. Symptoms and signs of this disease are often subtle and neither sensitive nor specific. Classic signs and symptoms (eg, cold intolerance, puffiness, decreased sweating, coarse skin) may not be present as commonly as was once believed. Many of the more common symptoms are nonspecific and difficult to attribute to a particular cause.

The following are symptoms of hypothyroidism:

  • Fatigue, loss of energy, and lethargy

  • Weight gain

  • Decreased appetite

  • Cold intolerance

  • Dry skin

  • Hair loss

  • Sleepiness

  • Muscle pain, joint pain, and weakness in the extremities

  • Depression

  • Emotional lability and mental impairment

  • Forgetfulness, impaired memory, and the inability to concentrate

  • Constipation

  • Menstrual disturbances and impaired fertility

  • Decreased perspiration

  • Paresthesias and nerve entrapment syndrome

  • Blurred vision

  • Decreased hearing

  • Fullness in the throat and hoarseness

Read more on the evaluation of patients with hypothyroidism.


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