Dietary factors, such as alcohol, hot beverages, caffeine, and spicy foods, can trigger the clinically relevant exacerbations of facial flushing and burning. In addition, some medications such as amiodarone and topical and nasal steroids, as well as high doses of vitamins B6 and B12, have been associated with symptom flare-ups.
Vasculature factors are thought to play a role in the pathogenesis of rosacea. One theory is that vasodilation of cutaneous blood vessels in the face is associated with the classic symptoms of redness and flushing.
Rhinophyma is more common in men than in women.
Learn more about the pathophysiology of rosacea.
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Cite this: William D. James. Fast Five Quiz: Pathogenesis and Presentation of Rosacea - Medscape - Jul 24, 2019.