Topical Photodynamic Therapy Clinical Practice Guidelines (2019)

British Association of Dermatologists and British Photodermatology Group

This is a quick summary of the guidelines without analysis or commentary. For more information, go directly to the guidelines by clicking the link in the reference.

May 06, 2019

Vulval Intraepithelial Neoplasia

Topical PDT can be considered for lesions of vulval intraepithelial neoplasia that are (1) unifocal, (2) nonpigmented, (3) without associated human papillomavirus infection, and (4) with lower grades of dysplasia.

Erythroplasia of Queyrat

Topical PDT can be considered in erythroplasia of Queyrat (Bowen disease of the glans penis); however, pain may be a limiting factor.

Cutaneous T‐Cell Lymphoma

Topical PDT can be considered for cutaneous T-cell lymphoma, in particular for early‐stage disease, cases with few localized lesions, and those in challenging sites (eg, skinfolds).

Extramammary Paget Disease

Topical PDT can be considered for extramammary Paget disease with thin or small lesions in situations in which (1) the Paget cell infiltrate is less dense and (2) there is limited adnexal involvement.

Topical PDT can be considered for extramammary Paget disease either before or after surgery.

An additional treatment option to be considered for extramammary Paget disease is carbon dioxide laser treatment prior to topical PDT.

Acne

Topical PDT can be considered for acne if standard treatments are ineffective or contraindicated.

Antimicrobial Treatment for Cutaneous Leishmaniasis, Fungal Infections, or Viral Warts

Conventional PDT can be considered for cutaneous leishmaniasis, in particular for cosmetically sensitive skin sites. Daylight PDT can also be considered for cutaneous leishmaniasis; however, several treatments may be required.

Topical PDT can be considered for recalcitrant viral warts.

Topical PDT should not be offered as a treatment option for fungal infections.

Psoriasis

Topical PDT should not be offered as a treatment option for psoriasis.

Actinic Cheilitis

Topical PDT can be considered for actinic cheilitis.

Insufficient Evidence to Support Any Recommendation

Evidence is insufficient to support any recommendation for alopecia areata, angiofibroma, Darier disease, folliculitis, granuloma annulare, hypertrophic scars, keratoacanthoma, lichenoid dermatoses, necrobiosis lipoidica, morphea and localized scleroderma, perioral dermatitis, photorejuvenation, porokeratosis, radiodermatitis, rosacea, sebaceous hyperplasia, vulval lichen sclerosus, vulvodynia, wound healing, or Zoon balanitis.

For more information go to Photodynamic Therapy for the Dermatologist.

For more Clinical Practice Guidelines, go to Guidelines.

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