Vulval Intraepithelial Neoplasia
Topical PDT can be considered for lesions of vulval intraepithelial neoplasia that are (1) unifocal, (2) nonpigmented, (3) without associated human papillomavirus infection, and (4) with lower grades of dysplasia.
Erythroplasia of Queyrat
Topical PDT can be considered in erythroplasia of Queyrat (Bowen disease of the glans penis); however, pain may be a limiting factor.
Cutaneous T‐Cell Lymphoma
Topical PDT can be considered for cutaneous T-cell lymphoma, in particular for early‐stage disease, cases with few localized lesions, and those in challenging sites (eg, skinfolds).
Extramammary Paget Disease
Topical PDT can be considered for extramammary Paget disease with thin or small lesions in situations in which (1) the Paget cell infiltrate is less dense and (2) there is limited adnexal involvement.
Topical PDT can be considered for extramammary Paget disease either before or after surgery.
An additional treatment option to be considered for extramammary Paget disease is carbon dioxide laser treatment prior to topical PDT.
Acne
Topical PDT can be considered for acne if standard treatments are ineffective or contraindicated.
Antimicrobial Treatment for Cutaneous Leishmaniasis, Fungal Infections, or Viral Warts
Conventional PDT can be considered for cutaneous leishmaniasis, in particular for cosmetically sensitive skin sites. Daylight PDT can also be considered for cutaneous leishmaniasis; however, several treatments may be required.
Topical PDT can be considered for recalcitrant viral warts.
Topical PDT should not be offered as a treatment option for fungal infections.
Psoriasis
Topical PDT should not be offered as a treatment option for psoriasis.
Actinic Cheilitis
Topical PDT can be considered for actinic cheilitis.
Insufficient Evidence to Support Any Recommendation
Evidence is insufficient to support any recommendation for alopecia areata, angiofibroma, Darier disease, folliculitis, granuloma annulare, hypertrophic scars, keratoacanthoma, lichenoid dermatoses, necrobiosis lipoidica, morphea and localized scleroderma, perioral dermatitis, photorejuvenation, porokeratosis, radiodermatitis, rosacea, sebaceous hyperplasia, vulval lichen sclerosus, vulvodynia, wound healing, or Zoon balanitis.
For more information go to Photodynamic Therapy for the Dermatologist.
For more Clinical Practice Guidelines, go to Guidelines.
Medscape © 2019 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Topical Photodynamic Therapy Clinical Practice Guidelines (2019) - Medscape - May 06, 2019.
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